Universities and research institutions

■Osaka University

Overview of activities

It is one of the leading universities in Japan with 11 undergraduate faculties, 16 graduate schools, 6 affiliated research institutes, and 2 affiliated hospitals. It is famous as a university that is strong in biotechnology related studies, especially immunity research. It has produced many researches from the Graduate School of Medicine and the Graduate School of Biological Function who have made remarkable contribution to research in the biomedical field. In addition, it is actively working on the initiatives for commercializing the research outcomes.

Main initiatives

At Osaka University, we proactively promote collaborative activities between industry, academia, and government, such as the establishment of "Joint Research Chairs" and "Research Alliance Laboratories," based around the Techno-Alliance Building of our Suita Campus, as we strive for the construction of a platform that can continuously produce new research topics leading to innovation.

Notes (appeal points etc.)

・Realization of inter-organizational cooperation among industry and academia through Joint Research Chairs and Research Alliance Laboratories.
・In addition to joint and contracted research systems, establishment of the Professional Advisory Services Consultation system which provides advice regarding scientific problem solving.
・Promotion of technology transfer of intellectual property created from research.
・Construction of a regional ecosystem through the creation and support of venture businesses started at the university under the "Public-Private Innovation Program."

Inquiries

Osaka University
TEL: +81-6-6877-5111

■Research Institute for Microbial Diseases, Osaka University(RIMD)

Overview of activities

Research Institute for Microbial Diseases (RIMD), Osaka University is the world's foremost institute for basic and clinical researches including microbiology, immunology, and oncology.

Main initiatives

Our mission is:
-To explore the mechanisms of the pathogenesis of microbes and elucidate how our immune system works against those pathogens.
-To understand our body system through genome analysis.
-To explore regulatory mechanisms in cancer cells and try to elucidate how cancer develops and progresses in our body.
-To develop new therapeutic approaches to diseases including infectious diseases, hereditary diseases, and autoimmune diseases.

Notes (appeal points etc.)

RIMD is certified as a "joint use/joint research location" by the Ministry of Education, Culture, Sports, Science and Technology. We maintain specialized facilities to study microbiology, immunology, and oncology, equipped with BSL2 and 3 laboratories in Animal Resource Center for Infectious Diseases and Central Laboratory for Biological Hazardous Microbes.

These research resources, facilities, and technologies are open to the research community and researchers are conducting collaborative projects with other research institutions and corporations.

Inquiries

■Osaka University Immunology Frontier Research Center(IFReC)

Overview of activities

The Immunology Frontier Research Center (IFReC), an international hub for immunology research, was established in 2007 as part of the World Premier International Research Center (WPI) Initiative program by the Ministry of Education, Culture, Sports, Science and Technology, Japan.By fusing immunology with biological imaging and bioinformatics, we have strived to cultivate new fields and conquer immune-related diseases. Reaching our 10th year in 2017, we are accelerating our expansion into medical science.

Main initiatives

・Elucidation of molecular mechanism of innate immunity
・Elucidation of the pathogenesis of immune related diseases
・Functional elucidation of regulatory T cells and translation into development of medicinal studies
・Elucidation of mechanisms of parasite infection and development of vaccines
・Elucidation of immune disease genes through bioinformatics
・Application of bioinformatics in the development of antibodies

Notes (strengths etc.)

A large number of foreign researchers work in IFReC and research environment and support system here meet the international standards.

We are working on explaining immune phenomenon using an 11.7 T MRI, two-photon excitation microscope, etc., and prediction of immune reaction making full use of bioinformatics. In addition, as an initiative to collaborate with companies, we are building an open innovation laboratory and actively conducting joint research.

Inquiries

Osaka University Immunology Frontier Research Center(IFReC)
TEL: +81-6-6879-4777 (Research Planning and Management Office)

■Osaka University Hospital

Overview of activities

Osaka University Hospital is one of the leading advanced medical development hospitals in Japan, and its philosophy is to provide high-quality medical care and contribute to nurturing of healthcare professionals and development of medical treatment.

Main initiatives

<Efforts toward accelerated development of innovative pharmaceuticals and implementation of special zone medical devices and pharmaceutical affairs strategy consultations as a clinical study core hospital.>

On August 7, 2015, Osaka University Hospital became the first hospital in the country to be approved by the Ministry of Health, Labour and Welfare as a clinical study core hospital under the Medical Care Act.Furthermore, from November 20 of the same year a "special zone medical devices and pharmaceutical affairs strategy consultations" was implemented targeting innovative medical device development projects in clinical study core hospitals within national strategic special zones, and on December 15, 2017 a further "accelerated development of innovative pharmaceuticals" was implemented targeting the development of pharmaceuticals.
Through these efforts we can expect to contribute to the expansion of Kansai's as well as Japan's medical industry.

Inquiries

Osaka University Hospital
TEL: +81-6-6879-5111

■Institute for Protein Research, Osaka University(IPR)

Overview of activities

Institute for Protein Research, Osaka University was founded in 1958 with the mission of shedding light and explaining the principles of life activities through fundamental research on proteins. As a shared facility and collaborative research center for protein research, it promotes joint research through use of facilities and equipment with domestic and overseas protein researchers including the industry, and it is also working on developing young human resources.

Main initiatives

・Joint use of SPring-8 synchrotron and beamline, group of ultra-high magnetic field nuclear magnetic resonance (NMR) equipment group and cryo-electron microscope. Development and publication of protein data bank (PDB) as a member of the Worldwide Protein Data Bank (wwPDB)
・Promotion of multi-scale structural life science in the Division of Multiscale integrative Protein Science which was established in 2016
・Conducting numerous protein research laboratories seminars and international seminars

Notes (appeal points etc.)

A large number of shared equipment is available at Institute for Protein Research, Osaka University that even corporate researchers can use without any cost (some of the equipment are available for a fee).

It is designated as a shared collaborative research center of the country and it is equipped with the management system for conduct high quality research that meets the international standards

Inquiries

■Osaka City University

Overview of activities

Osaka City University fulfills the role of think tank for urban Osaka, and it aims to conduct educational research and contribute to the community in the field of “urban studies”. Its goal is to promote the creation of new industries by consolidating the knowledge and wisdom of the university beyond the barriers of faculties, strengthening the brand power by creating new research and business areas, and developing new health areas.

Main initiatives

・Consolidating the knowledge and wisdom of the university and developing new health areas
・Development of next generation energy
・Base of urban disaster management

Notes (appeal points etc.)

The Center for Health Science Innovation has established a system to create new products and services through industry-university collaboration with enterprises, with medical science of fatigue and anti-fatigue as the core. It accelerates cross-innovation in different industries and fields by leveraging the strengths of a university located in a large city, offering the possibility to make use of its system for innovative device development.

Inquiries

URA Center
Osaka City University
TEL: +81-6-6605-3550

■Bio-Medical Forum, Osaka Prefecture University

Overview of activities

Osaka Prefecture University is an important member of the "Osaka Bio Strategy Promotion Council" established by Osaka Prefecture, and it has set up the Bio-Medical Forum for disseminating opinions and information on research strategy and initiatives for the bio industry.

Main initiatives

Bio-Medical Forum is comprised of three centers and two research laboratories, plans and proposes the strategy of biomedical research, and promotes good relationship between each member.

Inquiries

Research Administration Center
Bio-Medical Forum, Osaka Prefecture University
TEL: +81-7-2254-9128

■National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)

Overview of activities

By working to promote joint research which contributes to the development of medical products, medical devices, etc. as well as medicinal plants and other living resources and research and development conducted by private companies, etc., we aim for the creation of a foundation to improve medical product and device technology while also engaging in investigation and research into the maintenance and improvement of people's health and investigation and research into people's nutrition and other dietary matters, thereby working to improve and increase public health and contribute to the improvement of national health preservation. With this as our goal, we are engaged with the 6 projects to the right as well as operations based on the Health Promotion Act.

Main initiatives

・Research and support of drug discovery related to fundamental technologies
・Research and support of drug discovery related to biological resources
・Promotion of development of drugs and other products
・Surveys and studies pertaining to the maintenance and promotion of the health of people
・Surveys and studies regarding the nutrition and diet of people
・Nutrition physiology tests of food

Inquiries

■National Cerebral and Cardiovascular Center (NCVC)

Overview of activities

National Cerebral and Cardiovascular Center is a national center for advanced and specialized medical care and research. It promotes survey and research of cardiovascular disease and aims eradication of cardiovascular, setting its sights on advanced medicine. Our hospital is one of the world's leading centers conducting cooperative research in heart disease and cerebrovascular disease which were caused by the same risk factors in one facility by specialists of each field. Research institute clarifies pathology and develops technology to fulfill the clinical members’ needs. It enables problem solution more quickly that hospital and research institute work together. Moreover, research and development initiative center connects clinical field and research strongly.

Main initiatives

・Implementation of the greatest number of heart transplants in Japan
・Establishment of mobile telemedicine system
・A core facility of intravenous t-PA therapy and endovascular thrombectomy for acute stroke
・Basic research about pathogenesis and pathophysiology of cardiovascular diseases
・Development of artificial heart and blood vessels
・Cardiovascular surgery with less invasiveness
・Advanced check-up for cerebral and cardiovascular disease before onset

About moving

・In July 2019, NCVC will move to the site of Suita marshalling yard “KENTO,” directly connecting JR Kishibe Station.
・In KENTO, new NCVC is aiming to form a large medical cluster. Inaddition, it is also aiming more contribution toward community medicine with Suita Municipal Hospital, that is opening in 2018 in the same KENTO ground.
・New NCVC is focusing cardiovascular disease prevention, in addition to the forefront medical technique and research development with which NCVC has coped.
・“Open Innovation Center (OIC)” will be set in new NCVC to advance the cooperation with companies and universities for the purpose to create whole new medicine and medical machines.

Inquiries

■RIKEN Center for Biosystems Dynamics Research(BDR)

Overview of activities

In BDR Osaka campus we develop the underlying technology for analysis and simulation of molecular dynamics inside living cells in order to comprehensively understand the systemic properties essential to living things such as resilience and robust homeostasis, leading to the development of better treatments and medicines.

Technological developments

・Various high-performance microscopes for live cell imaging
・High throughput imaging technologies combined with robotic automation and artificial intelligence
・Organ transparency technology
・Noninvasive sleep analysis technique based on respiration
・Creating model animals economically and efficiently by triple-targeted CRISPR method
・New fluorescent probes that enable various types of live cell imaging
・Special purpose supercomputer for drug discovery simulation
・E-Cell, whole cell biochemistry simulation technology
・Glass microfluidics lab-on-a-chip embedded with fine flow paths

Inquiries

■AIST Kansai , National Institute of Advanced Industrial Science and Technology(AIST)

Overview of activities

AIST Kansai Center is working on developing diagnostic devices, drug discovery infrastructure technology, health and welfare equipment for "healthy society" centered on the biomedical research department.

Main initiatives

・Developing diagnostic devices such as ultrafast gene inspection system
・Bioproduction by genome editing and other technologies
・Studies and search marker for brain disease

Notes (appeal points etc.)

We are strengthening industry-academia collaboration through AIST Kansai informal gatherings.
We cooperate and collaborate with research institutions, government agencies, and companies including not only domestic but also international ones.

Inquiries

Industry-academia-government collaboration promotion office
AIST Kansai , National Institute of Advanced Industrial Science and Technology(AIST)
TEL: +81-7-2751-9681

Support Organization(Drug discovery etc.)

■Japan Agency for Medical Research and Development (AMED) Department of Innovative Drug Discovery and Development

Overview of activities

 By organizing Drug Discovery Support Network, we support biomedical R&D toward creation of novel drugs in cooperation with industrial and academic sectors. Moreover, we support development of innovative drugs and medication for orphan diseases through promotion of research activities regarding identification of drug targets and development of platform technologies for drug discovery as well as research for clinical application of medical technologies.

Inquiries

■Pharmaceuticals and Medical Devices Agency (PMDA) Kansai Branch

Overview of activities

Focusing mainly on academia and venture companies for the creation of innovative drugs, medical devices, regenerative medical products in Japan, we conduct regulatory science (RS) general consultations and RS strategic consultations (pre-consultation meeting) where we provide guidance and advice regarding planning the designs of studies and clinical trials which are required at the early stage of development. We can also provide advice regarding clinical trials and application materials in interviews utilizing the high-performance video conferencing systems connecting our Tokyo HQ and Kansai branch. Furthermore, we conduct investigations into whether the manufacturing facilities and manufacturing and quality controls of medical products, etc. comply with GMP/QMS/GCTP, etc.

Inquiries